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pentobarbital will lessen the extent or effect of alosetron by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unfamiliar.pentobarbital will minimize the extent or influence of hydrocortisone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.pentobarbital raises toxicity of buprenorphine, prolo